Journal article
The influence of sexual activity on the vaginal microbiota and Gardnerella vaginalis clade diversity in young women
LA Vodstrcil, J Twin, SM Garland, CK Fairley, JS Hocking, MG Law, EL Plummer, KA Fethers, EPF Chow, SN Tabrizi, CS Bradshaw
Plos One | Published : 2017
Abstract
Objectives To examine the influence of sexual activity on the composition and consistency of the vaginal microbiota over time, and distribution of Gardnerella vaginalis clades in young women. Methods Fifty-two participants from a university cohort were selected. Vaginal swabs were self-collected every 3-months for up to 12 months with 184 specimens analysed. The vaginal microbiota was characterised using Roche 454 V3/4 region 16S rRNA sequencing, and G. vaginalis clade typing by qPCR. Results A Lactobacillus crispatus dominated vaginal microbiota was associated with Caucasian ethnicity (adjusted relative risk ratio[ARRR] = 7.28, 95%CI:1.37,38.57,p = 0.020). An L. iners (ARRR = 17.51, 95%CI:2..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The research presented was funded by the National Health and Medical Research Council of Australia (APP1020457)